Preventing Childhood cancers: The Role of Folate

Preventing Childhood cancers: The Role of Folate

Scientific research suggests that adequate folate intake before and during pregnancy may help reduce the risk of childhood leukemia, particularly acute lymphoblastic leukemia (ALL), the most common type. Folate plays a vital role in DNA synthesis and repair, and ensuring sufficient levels may support healthy cell development in children.

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The Evidence

Studies indicate that countries with mandatory folic acid fortification have observed stable or declining childhood leukemia rates. The United States and Canada implemented folic acid fortification in the late 1990s, primarily to prevent neural tube defects. However, researchers later found potential protective effects against leukemia. Other countries, including Chile, Argentina, Brazil, Australia, and New Zealand, have also adopted fortification policies with similar benefits.

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Why Folate Matters

Folate (vitamin B9) is essential for DNA formation and cell growth. Its role in neural tube defect prevention is well-known, but studies now show that folate also helps protect against genetic mutations linked to childhood leukemia.

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How to Get Enough Folate

• Dietary Sources: Folate-rich foods include fortified cereals, leafy greens, citrus fruits, beans, and legumes. While these are important, they may not provide enough folate alone.

• Supplements: Health experts recommend taking a prenatal vitamin with at least 600 mcg of folic acid for at least one year before and during pregnancy.

• Fortified Foods: Many flours, breads, pastas, and breakfast cereals are enriched with folic acid, providing an additional source of this essential nutrient.​

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What the Research Shows

• Countries with mandatory folic acid fortification have seen lower rates of childhood leukemia.

• Mothers who took folic acid supplements before and during pregnancy had a reduced risk of leukemia in their children.​

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Our Mission

KoaStrong is committed to raising awareness and advocating for childhood leukemia prevention by encouraging women of reproductive age to prioritize folate intake. Through education, advocacy, and partnerships with healthcare providers, we aim to reduce childhood leukemia incidence and protect future generations.

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What You Can Do

• Talk to Your Doctor: Ask about folate supplementation if you're planning a pregnancy.

• Spread Awareness: Share this life-saving information with your community.

​Learn more about how you can support primary prevention efforts and share this vital message with your community.